TARGET AUDIENCE
The educational activity is directed to family and internal medicine physicians, physician assistants, and nurse practitioners who are registered with the DEA and eligible to prescribe all opioid analgesics, as well as non-prescribers who manage patients receiving opioid analgesic therapy, nonpharmacologic therapies, and nonopioid medication therapies for pain.

LEARNING OBJECTIVES
Through the application of the strategies, tools, and resources shared in this education, learners will demonstrate improvements in their confidence, knowledge, and skills to:

• Describe the fundamental concepts of pain management, including definitions and mechanisms of pain, with consideration of mental health factors
• Recognize how to assess patients in pain, identify risk factors for substance use disorders, and recognize co-occurring mental health conditions and who could benefit from behavioral health services
• Compare and contrast the range of therapeutic options for managing pain, including nonpharmacologic approaches, pharmacologic (non-opioid and opioid analgesics) therapies, and behavioral health interventions
• Integrate opioid analgesics and behavioral health strategies into a comprehensive pain treatment plan individualized to the needs of the patient, evaluating for functional and psychological improvement
• Assess how to safely and effectively manage patients on opioid analgesics in acute and chronic pain settings, including initiating therapy, titrating, and discontinuing use of opioid analgesics, with a focus on discontinuation of opioids incorporating mental health screening and behavioral interventions throughout treatment
• Identify counseling strategies for patients and caregivers about the safe use of opioid analgesics, including proper storage and disposal, while addressing potential mental health impacts and behavioral medicine approaches
• Identify approaches to counsel patients and caregivers about the use of naloxone for opioid overdose, considering the psychological aspects of overdose prevention and response
• Assess when referral to a pain specialist or mental health professional is appropriate within a multidisciplinary approach to pain management
• Summarize the fundamental elements of addiction medicine (ie, diagnosis, prevention, evaluation, treatment, and recovery of patients with opioid use disorder) and its intersection with mental health and behavioral health
• Recall how to identify and manage patients with opioid use disorder (OUD), incorporating behavioral health approaches and addressing co-occurring mental health disorders
• Identify current information about safe opioid practices and current federal and state regulations, national guidelines, professional organization and medical specialty guidelines on treating pain and prescribing opioids
• Describe the use of naloxone and the importance of its availability for use by patients and caregivers in the community and home

ACTIVITY DIRECTORS

Amy Zack, MD
Vice-Chief of Education, Eastern Submarket
Physician, Family Medicine, Southpointe Medical Center
Assistant Professor
Cleveland Clinic Lerner College of Medicine
Cleveland Clinic
Assistant Professor
Ohio University Heritage College of Osteopathic Medicine
Cleveland, OH

Robert Bales, MD
Assistant Professor of Family Medicine
Cleveland Clinic Lerner College of Medicine
Cleveland, OH

FACULTY

Akhil Anand, MD
Clinical Assistant Professor of Psychiatry
Cleveland Clinic Lerner College of Medicine
Cleveland, OH

Pavan Tankha, DO
Medical Director, Center for Comprehensive Pain Recovery
Neurological Institute
Cleveland Clinic
Cleveland, OH

ADDITIONAL PLANNERS/REVIEWERS

Jessica Benovic, CNP
Center for Adult Behavioral Health
Cleveland Clinic
Cleveland, OH

Jessica Toland, PA
Internal Medicine
Cleveland Clinic
Cleveland, OH

INSTRUCTIONS FOR PARTICIPATION AND REQUESTING CREDIT
There are no fees for participating and receiving credit for this activity. Successful completion is achieved by reviewing the CE information, completing the pre-test, completing the activity, and completing the post-test and evaluation form. A score of at least 75% on the posttest is required to successfully complete this activity. The participant may take the test until successfully passed.

ACCREDITATION STATEMENT

In support of improving patient care, Cleveland Clinic Center for Continuing Education is jointly accredited by the Accreditation Council for Continuing Medical Education (ACCME), the Accreditation Council for Pharmacy Education (ACPE), and the American Nurses Credentialing Center (ANCC) to provide continuing education for the health care team.

CREDIT DESIGNATION

American Medical Association (AMA)

The Cleveland Clinic Center for Continuing Education designates this enduring material for a maximum of 2.0 AMA PRA Category 1 Credit(s)™. Physicians should claim only the credit commensurate with the extent of their participation in the activity.

Participants claiming CME credit from this activity may submit the credit hours to the American Osteopathic Association for Category 2 credit.

American Nurses Credentialing Center (ANCC)

Nurses
Cleveland Clinic Center for Continuing Education designates this enduring activity for a maximum of 2.0 ANCC contact hours.

American Academy of PAs (AAPA)

Physician Assistants
Cleveland Clinic Center for Continuing Education has been authorized by the American Academy of PAs (AAPA) to award AAPA Category 1 CME credit for activities planned in accordance with AAPA CME Criteria. This activity is designated for 2.0 AAPA Category 1 CME credit. Approval is valid until 10/31/2026. PAs should only claim credit commensurate with the extent of their participation.

DISCLOSURE POLICY

In accordance with the Standards for Integrity and Independence issued by the Accreditation Council for Continuing Medical Education (ACCME), Cleveland Clinic Center for Continuing Education requires resolution of all faculty conflicts of interest to ensure CME activities are free of commercial bias. All relevant financial relationships have been mitigated.

The following faculty members have indicated that they may have a relationship which, in the context of their contribution, could be perceived as a potential conflict of interest.

To ensure mitigation of conflicts of interest, content was reviewed by a non-conflicted reviewer to ensure that it is not commercially biased, was fair-balanced, and is based on scientific evidence and/or clinical reasoning.

Robert Bales, MD
ROMTech—Private Ownership or Partnership
* This relationship was reviewed, and the company’s business lines are unrelated to the content of this activity. ACCME exception criteria applies.

Indivior Inc.—Advisor/Review Panel Participant

All other individuals have indicated no relationship, which in the context of their involvement, could be perceived as a potential conflict of interest.

Cleveland Clinic Center for Continuing Education and The France Foundation staff report no relevant financial relationships to disclose.

ACKNOWLEDGMENT

This activity is supported by an independent educational grant from the Opioid Analgesic REMS Program Companies.

Please see www.opioidanalgesicrems.com/Resources/Docs/List_of_RPC_Companies.pdf for a listing of REMS Program Companies. This activity is intended to be fully compliant with the Opioid Analgesic REMS education requirements issued by the U.S. Food and Drug Administration (FDA).

Disclaimer
The France Foundation and ArcheMedX present this information for educational purposes only. The content is provided solely by faculty who have been selected because of recognized expertise in their field. Participants have the professional responsibility to ensure that products are prescribed and used appropriately based on their own clinical judgment and accepted standards of care. The France Foundation, ArcheMedX, and the commercial supporter(s) assume no liability for the information herein.

COPYRIGHT INFORMATION
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• The materials are to be used solely for personal, noncommercial, informational, and educational purposes. The materials are not to be modified. They are to be distributed in the format provided with the source clearly identified. The copyright information or other proprietary notices may not be removed, changed, or altered.
• Materials may not be published, uploaded, posted, or transmitted (other than as set forth herein) without The France Foundation's prior written permission

PRIVACY POLICY
The France Foundation protects the privacy of personal and other information regarding participants and educational collaborators. The France Foundation will not release personally identifiable information to a third party without the individual's consent, except when such information is required for reporting purposes to the ACCME.

The France Foundation maintains physical, electronic, and procedural safeguards that comply with federal regulations to protect against the loss, misuse, or alteration of information that we have collected from you.

Additional information regarding The France Foundation’s Privacy Policy can be viewed at https://www.francefoundation.com/privacy.

CONTACT INFORMATION
If you have questions about this CME activity, please contact The France Foundation at 860-434-1650 or info@francefoundation.com.