TARGET AUDIENCE
This educational activity is intended for clinicians (physicians, pharmacists, nurses, and other clinical professionals), including those specializing in cardiology (general cardiologists, heart failure nurses, heart failure specialists, echocardiographers, nuclear cardiologists, and electrophysiologists), primary care clinicians (MDs/Dos, NPs, and PAs), and other specialists who may encounter patients with potential or confirmed ATTR-CM, such as hospitalists, geriatricians, emergency medicine professionals, and neurologists. 

PROGRAM OVERVIEW
This program offers a comprehensive overview of amyloidosis, focusing on ATTR-CM and its various phenotypes. It covers epidemiology and disparities in care based on geography, race, and gender. Learners will gain insights into common symptoms to help identify potential cases. Through clinical case discussions, the program will outline key steps in assessing hATTR-CM, including recognizing heart failure patients who should be evaluated for amyloidosis, accessing genetic testing resources, and supporting patients considering genetic testing. Additionally, it provides tools for effective patient communication about testing and results, including guidance on discussing findings with family members.

Upon completion of this activity, the learners should be able to:

• Identify patients with heart failure who should be assessed for possible amyloidosis work-up 
• Describe to patients with ATTR-CM how genetic testing may impact their disease management  
• Outline steps and available resources for genetic testing for patients with ATTR-CM 

FACULTY
Kevin Alexander, MD, FACC, FHFSA
Assistant Professor
Cardiovascular Medicine
Stanford Health Care Palo Alto, CA

PLANNING COMMITTEE
Kevin Alexander, MD, FACC, FHFSA
Assistant Professor
Cardiovascular Medicine
Stanford Health Care Palo Alto, CA

Emily Brown, MGC, CGC
Genetic Counselor
Johns Hopkins Center of Inherited Diseases
Johns Hopkins Medicine
Baltimore, MD

Newton Wiggins, MD, FACC, FHRS
Cardiologist
CommonSpirit Health
The Chattanooga Heart Institute
Chattanooga, TN

This activity is jointly provided by The France Foundation and the National Society of Genetic Counselors.

ACCREDITATION STATEMENT

In support of improving patient care, this activity has been planned and implemented by The France Foundation and the National Society of Genetic Counselors. The France Foundation is jointly accredited by the Accreditation Council for Continuing Medical Education (ACCME), the Accreditation Council for Pharmacy Education (ACPE), and the American Nurses Credentialing Center (ANCC) to provide continuing education for the health care team.

CREDIT DESIGNATION

Physicians

The France Foundation designates this enduring activity for a maximum of 1.0 AMA PRA Category 1 Credit(s)™. Physicians should claim only the credit commensurate with the extent of their participation in the activity.

Nurses

The France Foundation designates this activity for 1.0 contact hours.

All other healthcare professionals completing this course will be issued a statement of participation.

DISCLOSURE POLICY
In accordance with the ACCME Standards for Integrity and Independence in Accredited Continuing Education, The France Foundation (TFF) and The National Society of Genetic Counselors (NSGC) require that individuals in a position to control the content of an educational activity disclose all relevant financial relationships with any commercial entity. TFF and NSGC resolve all conflicts of interest to ensure independence, objectivity, balance, and scientific rigor in all their educational programs.

Furthermore, TFF and NSGC seek to verify that all scientific research referred to, reported, or used in a CME/CE activity conforms to the generally accepted standards of experimental design, data collection, and analysis. TFF and NSGC are committed to providing learners with high-quality CME/CE activities that promote improvements in health care and not those of a commercial interest.

Planning committee members, faculty, reviewers, and activity staff have disclosed the following relevant financial relationships. All relevant financial relationships listed have been mitigated.

TFF and NSGC requires CME faculty (speakers) to disclose when products or procedures being discussed are off label, unlabeled, experimental and/or investigational, and any limitations on the information that is presented, such as data that are preliminary, or that represent ongoing research, interim analyses, and/or unsupported opinion. Faculty in this activity may discuss information about pharmaceutical agents that are outside of US Food and Drug Administration approved labeling.

This information is intended solely for continuing medical education and is not intended to promote off-label use of these medications. TFF and NSGC does not recommend the use of any agent outside of the labeled indications. If you have questions, contact the Medical Affairs Department of the manufacturer for the most recent prescribing information.

This activity is supported by independent medical educational grants from Pfizer and BridgeBio.

The France Foundation and the National Society of Genetic Counselors use this information for educational purposes only. The content is provided solely by faculty who have been selected because of recognized expertise in their field. Participants have the professional responsibility to ensure that products are prescribed and used appropriately on the basis of their own clinical judgment and accepted standards of care. The France Foundation, the National Society of Genetic Counselors, and the commercial supporter(s) assume no liability for the information herein.

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