Welcome to the 2007 CRESCENT™ Resource Module. On this page
you will find the presentation files and corresponding reference list.

Physiology of Calcium and Phosphorus Metabolism Pathophysiology of Secondary HPT Biochemical and Clinical Outcomes of Therapies for Secondary HPT

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CRESCENT™ is an educational initiative designed to provide health care professionals with continuing medical education to increase the understanding of the physiology, pathophysiology, and treatment of secondary hyperparathyroidism (sHPT) in patients with chronic kidney disease (CKD).

This educational activity is sponsored by The France Foundation, and is supported by an educational donation provided by Amgen.

Educational Need
Chronic kidney disease (CKD) affects 8.3 million people in the United States. According to the National Kidney Foundation (NKF), 700,000 patients with CKD suffer from severely reduced kidney function or end-stage kidney failure. Among those, 300,000 require chronic maintenance hemodialysis, and 70,000 new patients enter dialysis programs each year. Additionally, a majority of these patients suffer from disorders of bone and mineral metabolism, including secondary hyperparathyroidism (sHPT), disorders of calcium and phosphorus metabolism, and soft tissue and vascular calcification. Alarmingly, the NKF predicts the number of patients with sHPT will double by 2010.

CKD, with the frequent complication of sHPT, thus represents a major medical problem in the US. Recent research has identified new approaches for managing the progression of sHPT. The CRESCENT initiative will present these new findings to physicians and other health care practitioners who care for patients with CKD. This educational activity will provide forums for the exchange of ideas that will help physicians to better manage patients with CKD and improve outcomes.

Target Audience
This educational activity is intended for nephrologists.

Educational Activity Objectives
Upon completion of this activity, the participants should be able to:
  • Explain the roles of Vitamin D and PTH in regulating serum calcium levels
  • Explain the link between biochemical changes in sHPT associated with CKD and increased morbidity and mortality
  • Discuss the different therapies for the disorders of PTH and mineral metabolism in CKD, review the data on clinical outcomes, and apply these therapies to clinical practice
Accreditation
The France Foundation is accredited by the Accreditation Council for Continuing Medical Education to provide continuing medical education for physicians.

Designation Statement
The France Foundation designates this educational activity for a maximum of 1.5 AMA PRA Category 1 Credits™. Physicians should only claim credit commensurate with the extent of their participation in the activity.

Disclaimer
The France Foundation presents this information for educational purposes only. The content is provided solely by faculty who have been selected because of recognized expertise in their field. Participants have the professional responsibility to ensure that products are prescribed and used appropriately on the basis of their own clinical judgment and accepted standards of care. The France Foundation and Amgen assume no liability for the information herein.

Faculty Information
Please go to Faculty Information to learn more about the faculty members and their pertinent disclosures.

Commercial Support Acknowledgement
This activity is supported by an educational donation provided by Amgen.

Release/Expiration Dates
This activity is eligible for CME credit from July 2007 through July 31, 2008.

Organization of the 2007 CRESCENT™ Resource Module
The 2007 CRESCENT™ Resource Module which consists of PowerPoint® slides with speaker notes should take approximately 1.5 hours to complete. The participant should complete the following, in the order listed below.
  • Read the objectives and other introductory information herein
  • View the material in the Resource Module/CD-ROM
  • Complete the Attestation/Evaluation Form/CME Posttest
  • To receive CME credit, fax or mail the completed forms to The France Foundation
  • Participants who complete the Attestation/Evaluation Form/CME Posttest will be issued a CME certificate within one month of submission to The France Foundation

Participants have the opportunity to comment on the quality of the instructional process, the perception of enhanced professional effectiveness, the perception of commercial bias, and his or her views on future educational needs. To receive credit for this activity, follow the instructions provided on the Attestation/Evaluation Form/CME Posttest. CME credit will be valid through July 31, 2008.

For further information or additional copies, please contact:
The France Foundation
Attn: CRESCENT™ Secretariat
230 Shore Road, Suite 202
Old Lyme, Connecticut 06371
Toll free: 1-866-856-1998
Fax: 1-860-434-5390